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When: 7:30 p.m
TV: NBC
Line: Saints by 5½
Key stat: The Saints had an NFL-leading 26 interceptions in 2009, five returned for touchdowns, also a league high.
Lowdown: Many will tune in to see how Vikings quarterback Brett Favre, 40, fares in launching his 20th season. With his tender ankle and a thin receiving corps, it's doubtful he can get at least 40 receptions from six players again. Drew Brees (4,388 yards passing, 34 touchdowns in 2009) and the Saints probably don't mind being under the radar, knowing how tough it is to achieve repeat championships. The offense is loaded, and if the big-play defense can hold up until safety Darren Sharper (knee) returns, New Orleans should stay with the elite.
Prediction: Saints 27-20
— Compiled by John Rodino
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